CAMKK2 Antibody - Cat. #: CSB-PA582406

SKU: CSB-PA582406

Size :100ul

Clone Number:

Aliases:Calcium/calmodulin dependent protein kinase beta antibody; Calcium/calmodulin dependent protein kinase kinase 2 antibody; Calcium/calmodulin dependent protein kinase kinase 2 beta antibody; Calcium/calmodulin dependent protein kinase kinase beta antibody; Calcium/calmodulin-dependent protein kinase kinase 2 antibody; Calcium/calmodulin-dependent protein kinase kinase beta antibody; CaM kinase kinase beta antibody; CaM KK beta antibody; CaM-kinase kinase 2 antibody; CaM-kinase kinase beta antibody; CaM-KK 2 antibody; CaM-KK beta antibody; CaMKK 2 antibody; CAMKK antibody; CaMKK beta antibody; CAMKK beta protein antibody; Camkk2 antibody; CAMKKB antibody; KKCC2_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96RR4

Immunogen:Synthesized peptide derived from internal of Human CAMKK2.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca2+ signals By similarity. Seems to be involved in hippocampal activation of CREB1 By similarity. May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.

Hsu L.-S., J. Biol. Chem. 276:31113-31123(2001).
Anderson K.A., J. Biol. Chem. 273:31880-31889(1998).
Ishikawa Y., FEBS Lett. 550:57-63(2003).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CAMKK2

Research Areas:Cancer;Signal transduction