Calpain 2(Phospho Ser50) Rabbit Polyclonal Antibody

SKU: BT-AP06807

Size:100μL

Background:The calpains| calcium-activated neutral proteases| are nonlysosomal| intracellular cysteine proteases. The mammalian calpains include ubiquitous| stomach-specific| and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large| catalytic subunits associated with a common small| regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme| calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.

Research_area:Cancer; Cell biology; Metabolism; Signal transduction

Target_protein:CAPN2

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Calpain 2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):77000

UniProt accession:Human: P17655; Mouse: O08529; Rat: Q07009

Synonyms:Calpain 2 ;Phospho Ser50; Calpain-2 catalytic subunit; EC 3.4.22.53; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; Calpain large polypeptide L2; Calpain-2 large subunit; Millimolar-calpain; M-calpain

GeneID:Human: 824; Mouse: 12334; Rat: 29154