Bovine SPRY domain-containing SOCS box protein 1,SPSB1 ELISA KIT

SKU: E0134Bo

Size:96Tests

Background:Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (By similarity). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (By similarity). {ECO:0000250|UniProtKB:Q96BD6}.

Research_area:

Applications:ELISA

Target_protein:SPSB1

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.34ng/ml

Detection range:0.63-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:SPRY domain-containing SOCS box protein 1

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q5E9X6

MASS(Da):30811

GeneID:504407

Synonyms:SPSB1 SSB1

Gene names:SPSB1

Standard solution:80ng/ml