Bovine Histone Deacetylase 8,HDAC8 ELISA KIT

SKU: E0047Bo

Size:96Tests

Background:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:HDAC8

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.12ng/ml

Detection range:0.25-16ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Histone Deacetylase 8

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q0VCB2

MASS(Da):41683

GeneID:540666

Synonyms:HDAC8

Gene names:HDAC8

Standard solution:32ng/ml