Birc5 Antibody - Cat. #: CSB-PA002706HA01MO

SKU: CSB-PA002706HA01MO

Size :50ug

Clone Number:

Aliases:Birc5 antibody; Api4 antibody; Iap4Baculoviral IAP repeat-containing protein 5 antibody; Apoptosis inhibitor 4 antibody; Apoptosis inhibitor survivin antibody; TIAP antibody

Product Type:Polyclonal Antibody

Immunogen Species:Mus musculus (Mouse)

UniProt ID:O70201

Immunogen:Recombinant Mouse Baculoviral IAP repeat-containing protein 5 protein (1-140AA)

Raised in:Rabbit

Species Reactivity:Mouse, Human

Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background:Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Birc5

Research Areas:Others