Biotin Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173]

SKU: GBS-F1114B

Size:100μg

Storage:This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD183;CXCR3

Target Synonym:C-X-C chemokine receptor type 3;CD183/CXCR3;CXC-R3;CXCR-3;Cxcr3;IP-10 receptor;Interferon-inducible protein 10 receptor

Research Areas:Immunology;Innate Immunity

Conjugation:Biotin

Host:Armenian Hamster

Species reactivity:Mouse

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype:Armenian Hamster IgG

Clonality:Monoclonal

Clone NO.:CXCR3-173

UNIProt ID:O88410

Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Concentration:0.5 mg/mL

Control catalog number:E-AB-F09853B

Immunogen:

Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Purification method:

Dilution:

GeneID:12766