BAG3 Polyclonal Antibody

SKU: E-AB-40660

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: BAG3

Target Synonym: BAG family molecular chaperone regulator 3 ;BAG-3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BIS

Research Areas: Cancer;Cell Biology;Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O95817

Accession:

Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

Concentration: 1 mg/mL

Immunogen: Recombinant Human BAG3 protein expressed by E.coli

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:500-1:1000

Calculated MW: 62 kDa

ObservedMW: 80 kDa