BAAT Antibody - Cat. #: CSB-PA613484LA01HU

SKU: CSB-PA613484LA01HU

Size :50ug

Clone Number:

Aliases:FLJ20300 antibody; BAAT antibody; BAAT_HUMAN antibody; BACAT antibody; BAT antibody; Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) antibody; Bile acid CoA:amino acid N acyltransferase antibody; Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase antibody; Bile acid Coenzyme A: amino acid N acyltransferase antibody; Bile acid-CoA:amino acid N-acyltransferase antibody; Glycine N choloyltransferase antibody; Glycine N-choloyltransferase antibody; Long chain fatty acyl CoA hydrolase antibody; Long-chain fatty-acyl-CoA hydrolase antibody; MGC104432 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14032

Immunogen:Recombinant Human Bile acid-CoA:amino acid N-acyltransferase protein (313-400AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background:Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:BAAT

Research Areas:Cancer; Metabolism; Signal transduction