ATXN3 Polyclonal Antibody

SKU: E-AB-52456

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:ATXN3

Target Synonym:AT3;Ataxin 3;ataxin 3 variant h;ataxin 3 variant m;ataxin 3 variant ref;Ataxin-3;ATX3;ATX3;ATXN3;EC 3.4.22.;JOS;Josephin;Machado Joseph disease (spinocerebellar ataxia 3;olivopontocerebellar ataxia 3;autosomal dominant;ataxin 3);Machado Joseph disease;Machado Joseph disease protein 1;Machado-Joseph disease protein 1;Machado-Joseph disease protein 1 homolog;MJD;MJD gene;MJD1;Olivopontocerebellar ataxia 3;OTTHUMP00000221583;OTTHUMP00000221585;OTTHUMP00000221586;OTTHUMP00000221587;OTTHUMP00000231995;OTTHUMP00000231997;Rsca3;SCA3;SCA3 gene;Spinocerebellar ataxia type 3 protein

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P54252

Accession:

Background:Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Concentration:0.4 mg/mL

Immunogen:Fusion protein of human ATXN3

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:40-1:200

Calculated MW:

ObservedMW: