ATG5 (3C7) Mouse mAb

SKU: EM1374

Size: 100μL

Source:Mouse

Applications:WB, IHC

Reactivity:Human, Mouse, Rat

Dilution:WB 1:5,000-10,000 IHC 1:100-200

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):55kDa

Human_gene_id:9494

Human_swiss_prot_no:Q9H1Y0

Subcellular_location:Cytoplasm, Membrane

Other_name:APG5, APG5L, ASP, Autophagy protein 5 antibody

Background:Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.