ATG1 Antibody - Cat. #: CSB-PA738902LA01CZI

SKU: CSB-PA738902LA01CZI

Size :50ug

Clone Number:

Aliases:ATG1 antibody; CAGL0L06006g antibody; Serine/threonine-protein kinase ATG1 antibody; EC 2.7.11.1 antibody; Autophagy-related protein 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Candida glabrata

UniProt ID:Q6FL58

Immunogen:Recombinant Candida glabrata Serine/threonine-protein kinase ATG1 protein (11-312AA)

Raised in:Rabbit

Species Reactivity:Candida glabrata

Tested Applications:ELISA

Background:Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ATG1

Research Areas:Others