ASGR2 Monoclonal Antibody

SKU: BT-MCA2389

Size:100μL

Background:This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research_area:Others

Target_protein:ASGR2

applications:IHC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:2C6D11

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:ASGR2

Immunogen:Purified recombinant fragment of human ASGR2 (AA: 80-311) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):35kDa

UniProt accession:P07307

Synonyms:HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2

GeneID:433