AR Polyclonal Antibody

SKU: E-AB-70112

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:AR

Target Synonym:AIS;ANDR;Androgen nuclear receptor variant 2;Androgen receptor (dihydrotestosterone receptor;testicular feminization;spinal and bulbar muscular atrophy;Kennedy disease);Androgen receptor;androgen receptor splice variant 4b;AR;AR8;DHTR;Dihydro testosterone receptor;Dihydrotestosterone receptor (DHTR);Dihydrotestosterone receptor;HUMARA;HYSP1;KD;Kennedy disease (KD);NR3C4;Nuclear receptor subfamily 3 group C member 4 (NR3C4);Nuclear receptor subfamily 3 group C member 4;SBMA;SMAX1;Spinal and bulbar muscular atrophy (SBMA);Spinal and bulbar muscular atrophy;Testicular Feminization (TFM);TFM

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Developmental Biology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P10275;P19091;P15207

Accession:

Background:The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein.

Concentration:0.83 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse Androgen receptor

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:IHC 1:300-1:1000

Calculated MW:

ObservedMW: