APOO Antibody, HRP conjugated - Cat. #: CSB-PA001948LB01HU

SKU: CSB-PA001948LB01HU

Size :50ul

Clone Number:

Aliases:0610008C08Rik antibody; 1110019O03Rik antibody; Apolipoprotein O antibody; APOO antibody; APOO_HUMAN antibody; FAM121B antibody; Family with sequence similarity 121B antibody; MGC130105 antibody; MGC130106 antibody; MGC4825 antibody; My025 antibody; MYO25 antibody; OTTHUMP00000023073 antibody; Protein FAM121B antibody; RP23-272D10.2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BUR5

Immunogen:Recombinant Human MICOS complex subunit MIC26 protein (26-198AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:25764979). Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151). Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL (PubMed:16956892).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:APOO

Research Areas:Signal Transduction