APG7 Rabbit Polyclonal Antibody

SKU: BT-AP05821

Size:100μL

Background:This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions| including axon membrane trafficking| axonal homeostasis| mitophagy| adipose differentiation| and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.

Research_area:Cancer; Cardiovascular; Cell biology; Metabolism; Signal transduction

Target_protein:ATG7

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:APG7

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):77330

UniProt accession:Human: O95352; Mouse: Q9D906; Rat: Q641Y5

Synonyms:APG7; Ubiquitin-like modifier-activating enzyme ATG7; ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7; APG7-like; hAGP7; Ubiquitin-activating enzyme E1-like protein

GeneID:Human: 10533; Mouse: 74244; Rat: 312647