APC Monoclonal Antibody

SKU: BT-MCA2856

Size:100μL

Background:This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Research_area:Cell Biology

Target_protein:APC

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:1F7G2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:APC

Immunogen:Purified recombinant fragment of human APC (AA: 2644-2843) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):311.6kDa

UniProt accession:P25054

Synonyms:GS, DP2, DP3, BTPS2, DP2.5, PPP1R46

GeneID:324