Anti-WDR5 Antibody Picoband®

SKU: A01910-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: WDR5

Specificity:

Background: WD repeat-containing protein 5 is a protein that in humans is encoded by the WDR5 gene. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.

Immunogen: E.coli-derived human WDR5 recombinant protein (Position: Q25-D324).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Brown, S. A., Ripperger, J., Kadener, S., Fleury-Olela, F., Vilbois, F., Rosbach, M., Schibler, U. PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator. Science 308: 693-696, 2005. 2. El-Brolosy, M. A., Kontarakis, Z., Rossi, A., Kuenne, C., Gunther, S., Fukuda, N., Kikhi, K., Boezio, G. L. M., Takacs, C. M., Lai, S.-L., Fukuda, R., Gerri, C., Giraldez, A. J., Stainier, D. Y. R. Genetic compensation triggered by mutant mRNA degradation. Nature 568: 193-197, 2019. 3. Gori, F., Divieti, P., Demay, M. B. Cloning and characterization of a novel WD-40 repeat protein that dramatically accelerates osteoblastic differentiation. J. Biol. Chem. 276: 46515-46522, 2001.

Uniprot ID: P61964

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 37 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 11091

Protein Name: WD repeat-containing protein 5

Gene Full Name: WD repeat domain 5

Synonyms: BIG 3; BIG3; BMP2 induced 3 kb gene protein; SWD3; WD repeat containing protein 5; WD repeat domain 5; WDR5