Anti-TRAP1 Antibody Picoband®

SKU: A02426-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.1-0.25 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: TRAP1

Specificity:

Background: Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene. It is mapped to 16p13.3. This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. And this protein may function in regulating cellular stress responses. In addition, it was found that TRAP1 interacted with the N-terminal half of TNFR1. Also, TRAP1 interacted with the C-terminal ends of the proteins encoded by both multiple exostoses-causing genes, EXT1 and EXT2, but not with EXTL1 or EXTL3.

Immunogen: E.coli-derived human TRAP1 recombinant protein (Position: A618-H704).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Entrez Gene: TRAP1 TNF receptor-associated protein 1. 2. Felts SJ, Owen BA, Nguyen P, Trepel J, Donner DB, Toft DO (March 2000). The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties. J Biol Chem 275 (5): 3305–12. 3. Song HY, Dunbar JD, Zhang YX, Guo D, Donner DB (March 1995). Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor. J Biol Chem 270 (8): 3574–81.

Uniprot ID: Q12931

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 80 kDa

Calculated Molecular Weight: 38779 MW

Gene ID: 10131

Protein Name: Heat shock protein 75 kDa, mitochondrial

Gene Full Name: TNF receptor associated protein 1

Synonyms: HSP 75; HSP75; HSP90L; TNFR associated protein 1; TRAP 1; TRAP1