Anti-TEF1/TEAD-1/TEAD1 Antibody Picoband®

SKU: A03263-2

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: ELISA,WB

Application Details: Western blot, 0.25-0.5μg/ml, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: TEAD1

Specificity:

Background: Transcriptional enhancer factor TEF-1 also known as TEA domain family member 1 (TEAD1) and transcription factor 13 (TCF-13) is a protein that in humans is encoded by the TEAD1 gene. This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein s the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified.

Immunogen: E.coli-derived human TEF1/TEAD-1/TEAD1 recombinant protein (Position: D38-D426).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Blatt, C., DePamphilis, M. L. Striking homology between mouse and human transcription enhancer factor-1 (TEF-1). Nucleic Acids Res. 21: 747-748, 1993. 2. Chen, Z., Friedrich, G. A., Soriano, P. Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice. Genes Dev. 8: 2293-2301, 1994. 3. Fossdal, R., Jonasson, F., Kristjansdottir, G. T., Kong, A., Stefansson, H., Gosh, S., Gulcher, J. R., Stefansson, K. A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration). Hum. Molec. Genet. 13: 975-981, 2004.

Uniprot ID: P28347

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 50 kDa

Calculated Molecular Weight:

Gene ID: 7003

Protein Name: Transcriptional enhancer factor TEF-1

Gene Full Name: TEA domain transcription factor 1

Synonyms: TEAD1; TCF13; TEF1; Transcriptional enhancer factor TEF-1; NTEF-1; Protein GT-IIC; TEA domain family member 1; TEAD-1; Transcription factor 13; TCF-13