Anti-TARC/CCL17 Antibody Picoband®

SKU: PB9031

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Mouse

Applications: ELISA,WB

Application Details: Western blot, 0.1-0.5μg/ml, Mouse, -
ELISA, 0.1-0.5μg/ml, -

Gene Name: CCL17

Specificity: No cross reactivity with other proteins.

Background: Chemokine (C-C motif) ligand 17 (CCL17) is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). CCL17 is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. This chemokine specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. The gene for CCL17 is located on chromosome 16, in humans, along with other chemokines called CCL22 and CX3CL1. The standard used in this kit is recombinant human CCL17, consisting of 71 amino acids with the molecular weight of 8Kda.

Immunogen: E.coli-derived mouse TARC recombinant protein (Position: A34-P103). Mouse TARC shares 71% amino acid (aa) sequence identity with human TARC.

Clonality: Polyclonal

Contents: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg NaN3.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Imai T, Yoshida T, Baba M, Nishimura M, Kakizaki M, Yoshie O (1996). Molecular cloning of a novel T cell-ed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector. J. Biol. Chem. 271 (35): 21514–21. 2. Imai T, Baba M, Nishimura M, Kakizaki M, Takagi S, Yoshie O (1997). The T cell-ed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J. Biol. Chem. 272 (23): 15036–42. 3. Nomiyama H, Imai T, Kusuda J, Miura R, Callen DF, Yoshie O (1997). Assignment of the human CC chemokine gene TARC (SCYA17) to chromosome 16q13. Genomics 40 (1): 211–3. 4. Nomiyama H, Imai T, Kusuda J, Miura R, Callen DF, Yoshie O (1998). Human chemokines fractalkine (SCYD1), MDC (SCYA22) and TARC (SCYA17) are clustered on chromosome 16q13. Cytogenet. Cell Genet. 81 (1): 10–1.

Uniprot ID: Q9WUZ6

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 34 kDa

Calculated Molecular Weight: 10467 MW

Gene ID: 20295

Protein Name: C-C motif chemokine 17

Gene Full Name: C-C motif chemokine ligand 17

Synonyms: A 152E5.3; ABCD 2; C C motif chemokine 17; CC chemokine TARC; CCL17; SCYA17; Small inducible cytokine A17; TARC