Anti-Stanniocalcin 1/STC/STC1 Antibody

SKU: A03402

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: IHC,ELISA

Application Details: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: STC1

Specificity:

Background: STC1(Stanniocalcin 1), also called STC, which is encoded by the STC1 gene. By fluorescence in situ hybridization, Chang et al.(1998) mapped the STC1 gene to chromosome 8p21-p11.2. Wagner et al.(1995) found evidence of STC immunoreactivity in human kidney and serum, suggesting the existence of the hormone in mammals. Zhang et al.(1998) reported a constitutive expression of STC in terminally differentiated neurons. Bell et al.(2001) determined that STC1 was 1 of several transcripts upregulated by umbilical vein endothelial cells during capillary morphogenesis in 3-dimensional collagen matrices.

Immunogen: E.coli-derived human Stanniocalcin 1/STC/STC1 recombinant protein (Position: V34-A247).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Bell, S. E., Mavila, A., Salazar, R., Bayless, K. J., Kanagala, S., Maxwell, S. A., Davis, G. E. Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. J. Cell Sci. 114: 2755-2773, 2001. 2. Chang, A. C.-M., Jeffrey, K. J., Tokutake, Y., Shimamoto, A., Neumann, A. A., Dunham, M. A., Cha, J., Sugawara, M., Furuichi, Y., Reddel, R. R. Human stanniocalcin (STC): genomic structure, chromosomal localization, and the presence of CAG trinucleotide repeats. Genomics 47: 393-398, 1998. 3. Wagner, G. F., Guiraudon, C. C., Milliken, C., Copp, D. H. Immunological and biological evidence for a stanniocalcin-like hormone in human kidney. Proc. Nat. Acad. Sci. 92: 1871-1875, 1995. 4. Zhang, K., Westberg, J. A., Paetau, A., von Boguslawsky, K., Lindsberg, P., Erlander, M., Guo, H., Su, J., Olsen, H. S., Andersson, L. C. High expression of stanniocalcin in differentiated brain neurons. Am. J. Path. 153: 439-445, 1998.

Uniprot ID: P52823

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 75 kDa

Calculated Molecular Weight: 73109 MW

Gene ID: 6781

Protein Name: Stanniocalcin-1

Gene Full Name: stanniocalcin 1

Synonyms: stanniocalcin 1; STC; STC 1; STC1