Anti-SFRP2 Antibody Picoband®

SKU: A01752-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: Flow Cytometry,IF,ICC,WB

Application Details: Western blot, 0.1-0.25μg/ml, Human
Immunocytochemistry/Immunofluorescence, 2μg/ml, Human
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human

Gene Name: SFRP2

Specificity: No cross reactivity with other proteins.

Background: SFRP2 is also known as FRP-2, SARP1 or SDF-5. It is Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.?

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SFRP2, identical to the related mouse and rat sequences.

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Hao XW, et al. Epigenetic inactivation of secreted frizzled-related protein 2 in esophageal squamous cell carcinoma. World J Gastroenterol, 2012 Feb 14. 2. O'Hurley G, et al. The role of secreted frizzled-related protein 2 expression in prostate cancer. Histopathology, 2011 Dec. 3. Sui C, et al. Variation risks of SFRP2 hypermethylation between precancerous disease and colorectal cancer. Tumour Biol, 2014 Oct.

Uniprot ID: Q96HF1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 38 kDa

Calculated Molecular Weight:

Gene ID: 6423

Protein Name: Secreted frizzled-related protein 2

Gene Full Name: secreted frizzled related protein 2

Synonyms: FRP 2; FRP2; FRP-2; SARP 1; SARP1; SDF 5; sFRP 2; SFRP2; UNQ361/PRO697