Anti-Securin Monoclonal Antibody

SKU: M02099

Size: 100 μl

Storage: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Form: Liquid

Reactivity: Human

Applications: WB,IHC,ICC,IF,IP,Flow Cytometry

Application Details: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
IP 1:30
FC 1:50

Gene Name: PTTG1

Specificity:

Background:

Immunogen: A synthesized peptide derived from human Securin Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.

Clonality: Monoclonal

Contents: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Affinity-chromatography

Reconstitution:

Reference:

Uniprot ID: O95997

Host: Rabbit

Concentration: 0.5mg/ml

Conjugate:

Cross Reactivity:

Isotype: Rabbit IgG

Phospho_site:

Clone Number: Clone: ADFH-16

Observed Molecular Weight: 26 kDa

Calculated Molecular Weight: 16320 MW

Gene ID: 9232

Protein Name: Securin

Gene Full Name: PTTG1 regulator of sister chromatid separation, securin

Synonyms: EAP1; Esp1 associated protein; HPTTG; pituitary tumor transforming 1; PTTG; PTTG1; Securin; Tumor transforming protein 1; TUTR1