Anti-SEC61G Antibody Picoband®

SKU: A12389

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SEC61G

Specificity:

Background: Protein transport protein Sec61 subunit gamma is a protein that in humans is encoded by the SEC61G gene. The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified.

Immunogen: E.coli-derived human SEC61G recombinant protein (Position: M1-I64).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Greenfield, J. J. A., High, S. The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment. J. Cell Sci. 112: 1477-1486, 1999. 2. Hartmann, E., Sommer, T., Prehn, S., Gorlich, D., Jentsch, S., Rapoport, T. A. Evolutionary conservation of components of the protein translocation complex. Nature 367: 654-657, 1994. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 2/22/2005.

Uniprot ID: P60059

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 12 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 23480

Protein Name: Protein transport protein Sec61 subunit gamma

Gene Full Name: SEC61 translocon subunit gamma

Synonyms: Sec61 gamma subunit; SEC61G; SSS1