Anti-SAPS3/PPP6R3 Antibody Picoband®

SKU: A10833-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Monkey,Mouse,Rat

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Monkey, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PPP6R3

Specificity:

Background: Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit.

Immunogen: E.coli-derived human SAPS3/PPP6R3 recombinant protein (Position: R279-R848).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Nagase, T., Kikuno, R., Nakayama, M., Hirosawa, M., Ohara, O. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 7: 273-281, 2000. 2. Stefansson, B., Brautigan, D. L. Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets I-kappa-B-epsilon. J. Biol. Chem. 281: 22624-22634, 2006. 3. Twells, R. C. J., Metzker, M. L., Brown, S. D., Cox, R., Garey, C., Hammond, H., Hey, P. J., Levy, E., Nakagawa, Y., Philips, M. S., Todd, J. A., Hess, J. F. The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13. Genomics 72: 231-242, 2001.

Uniprot ID: Q5H9R7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 144 kDa

Calculated Molecular Weight:

Gene ID: 55291

Protein Name: Serine/threonine-protein phosphatase 6 regulatory subunit 3

Gene Full Name: protein phosphatase 6 regulatory subunit 3

Synonyms: PPP6R3; C11orf23; KIAA1558; PP6R3; SAPL; SAPS3; Serine/threonine-protein phosphatase 6 regulatory subunit 3; SAPS domain family member 3; Sporulation-induced transcript 4-associated protein SAPL