Anti-RASL12 Antibody Picoband®

SKU: A15197-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: RASL12

Specificity:

Background: Belonging to the small GTPase superfamily/Ras family, RASL12 is localized in the cellular membrane and cytoplasm. RASL12 has many important molecular functions including GTP binding, GTPase activity and nucleotide binding. The main biological function of this gene is to participate in the GTP catabolic process, signal transduction and small GTPase mediated signal transduction. RASL12 interacts with ACVR1, SMAD1, SMAD2, SMAD3 and SMURF2. Documented diseases associated with RASL12 include acute kidney tubular necrosis, intraepithelial neoplasm, retinitis, endometrial cancer, coronary artery disease and Huntington's disease.

Immunogen: E.coli-derived human RASL12 recombinant protein (Position: K7-K261). Human RASL12 shares 93.3% amino acid (aa) sequence identity with mouse RASL12.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Wistow, G., Bernstein, S. L., Ray, S., Wyatt, M. K., Behal, A., Touchman, J. W., ... & Peterson, K. (2002). Expressed sequence tag analysis of adult human iris for the NEIBank Project: steroid-response factors and similarities with retinal pigment epithelium. Mol Vis, 8(21), 185-195. 2. Barrios-Rodiles, M., Brown, K. R., Ozdamar, B., Bose, R., Liu, Z., Donovan, R. S., ... & Wrana, J. L. (2005). High-throughput mapping of a dynamic signaling network in mammalian cells. Science, 307(5715), 1621-1625. 3. Lipp, J. J., Marvin, M. C., Shokat, K. M., & Guthrie, C. (2015). SR protein kinases promote splicing of nonconsensus introns. Nature structural & molecular biology, 22(8), 611.

Uniprot ID: Q9NYN1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 30 kDa

Calculated Molecular Weight: 30,29,27 kDa

Gene ID: 51285

Protein Name: Ras-like protein family member 12

Gene Full Name: RAS like family 12

Synonyms: RASL12; RIS; Ras-like protein family member 12; Ras-like protein Ris