Anti-POMGNT2 Antibody Picoband®

SKU: A11987-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: POMGNT2

Specificity:

Background: This gene encodes a protein with glycosyltransferase activity although its function is not currently known.

Immunogen: E.coli-derived human POMGNT2 recombinant protein (Position: R40-K378). Human POMGNT2 shares 94.7% and 95% amino acid (aa) sequence identity with mouse and rat POMGNT2, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Endo, Y., Dong, M., Noguchi, S., Ogawa, M., Hayashi, Y. K., Kuru, S., Sugiyama, K., Nagai, S., Ozasa, S., Nonaka, I., Nishino, I. Milder forms of muscular dystrophy associated with POMGNT2 mutations. Neurol. Genet. 1: e33, 2015. Note: Electronic Article. 2. Manzini, M. C., Tambunan, D. E., Hill, R. S., Yu, T. W., Maynard, T. M., Heinzen, E. L., Shianna, K. V., Stevens, C. R., Partlow, J. N., Barry, B. J., Rodriguez, J., Gupta, V. A., and 10 others. Exome sequencing and functional validation in zebrafish identify GTDC2 mutations as a cause of Walker-Warburg syndrome. Am. J. Hum. Genet. 91: 541-547, 2012. 3. Yoshida-Moriguchi, T., Willer, T., Anderson, M. E., Venzke, D., Whyte, T., Muntoni, F., Lee, H., Nelson, S. F., Yu, L., Campbell, K. P. SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function. Science 341: 896-899, 2013.

Uniprot ID: Q8NAT1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 75 kDa

Calculated Molecular Weight:

Gene ID: 84892

Protein Name: Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

Gene Full Name: protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)

Synonyms: POMGNT2; AGO61; C3orf39; EOGTL; GTDC2; Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2; POMGnT2; Extracellular O-linked N-acetylglucosamine transferase-like; Glycosyltransferase-like domain-containing protein 2