Anti-PLD5 Antibody Picoband®

SKU: A14197-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PLD5

Specificity:

Background: Phospholipase D family, member 5 is a protein that in humans is encoded by the PLD5 gene. Inactive phospholipase D5 (PLD5) is a variant of the phospholipase D enzyme family that lacks catalytic activity due to mutations or alterations in critical amino acid residues. Despite its inactivity, PLD5 is believed to contribute to cellular processes such as lipid metabolism and membrane dynamics, highlighting its potential regulatory roles in cellular signaling pathways.

Immunogen: E.coli-derived human PLD5 recombinant protein (Position: K247-K517). Human PLD5 shares 95.9% amino acid (aa) sequence identity with mouse PLD5.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Liu, J., Li, J., Ma, Y., Xu, C., Wang, Y., & He, Y. (2021). MicroRNA miR-145-5p inhibits Phospholipase D 5 (PLD5) to downregulate cell proliferation and metastasis to mitigate prostate cancer. Bioengineered, 12(1), 3240-3251. 2. Anney, R., Klei, L., Pinto, D., Regan, R., Conroy, J., Magalhaes, T. R., ... & Gill, M. (2010). A genome-wide scan for common alleles affecting risk for autism. Human molecular genetics, 19(20), 4072-4082. 3. McCauley, J. L., Zuvich, R. L., Bradford, Y., Kenealy, S. J., Schnetz-Boutaud, N., Gregory, S. G., ... & Haines, J. L. (2009). Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. Genes & Immunity, 10(7), 624-630.

Uniprot ID: Q8N7P1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 69 kDa

Calculated Molecular Weight: 61,51,38,54 kDa

Gene ID: 200150

Protein Name: Inactive phospholipase D5

Gene Full Name: phospholipase D family member 5

Synonyms: PLD5; Inactive phospholipase D5; Inactive PLD 5; Inactive choline phosphatase 5; Inactive phosphatidylcholine-hydrolyzing phospholipase D5; PLDc