Anti-PIP4K2B Antibody Picoband®

SKU: A09390-2

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: PIP4K2B

Specificity:

Background: The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.

Immunogen: E.coli-derived human PIP4K2B recombinant protein (Position: D116-K360). Human PIP4K2B shares 98.8% and 97.6% amino acid (aa) sequence identity with mouse and rat PIP4K2B, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Castellino, A. M., Parker, G. J., Boronenkov, I. V., Anderson, R. A., Chao, M. V. A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase. J. Biol. Chem. 272: 5861-5870, 1997. 2. Ciruela, A., Hinchliffe, K. A., Divecha, N., Irvine, R. F. Nuclear targeting of the beta isoform of type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its alpha-helix 7. Biochem. J. 346: 587-591, 2000. 3. Lamia, K. A. Personal Communication. Boston, Mass. 8/26/2004.

Uniprot ID: P78356

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 50 kDa

Calculated Molecular Weight: 47 kDa

Gene ID: 8396

Protein Name: Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

Gene Full Name: phosphatidylinositol-5-phosphate 4-kinase type 2 beta

Synonyms: PI(5)P 4 kinase type II beta; PI5P4KB; PIP4K2B; PIP4KII beta; PIP5K2B; PIP5KIIB; PIP5KIIbeta