Anti-PHD2 / prolyl hydroxylase Monoclonal Antibody

SKU: M00415

Size: 100 μl

Storage: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Form: Liquid

Reactivity: Human

Applications: WB,IP

Application Details: WB 1:500-2000
IP 1:20

Gene Name: EGLN1

Specificity:

Background:

Immunogen: A synthesized peptide derived from human PHD2 / prolyl hydroxylase Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Clonality: Monoclonal

Contents: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Affinity-chromatography

Reconstitution:

Reference:

Uniprot ID: Q9GZT9

Host: Rabbit

Concentration: 0.5mg/ml

Conjugate:

Cross Reactivity:

Isotype: Rabbit IgG

Phospho_site:

Clone Number: Clone: ACEF-5

Observed Molecular Weight: 52 kDa

Calculated Molecular Weight: 10835 MW

Gene ID: 54583

Protein Name: Egl nine homolog 1

Gene Full Name: egl-9 family hypoxia inducible factor 1

Synonyms: C1orf12; ECYT3; Egl nine homolog 1; EGLN1; HIF PH2; HIF prolyl hydroxylase 2; HIFPH2; HPH 2; HPH2; PHD2; PHD2/EGLN1; PNAS 137; SM 20; SM20; ZMYND6