Anti-PGD Antibody Picoband®

SKU: A01623-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.1-0.25 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PGD

Specificity:

Background: 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human PGD recombinant protein (Position: D24-R447). Human PGD shares 93.9% and 92.9% amino acid (aa) sequence identity with mouse and rat PGD, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Benkmann, H.-G., Paik, Y. K., Chen, L. Z., Goedde, H. W. Polymorphism of 6-PGD in South Korea: a new genetic variant 6-PGD Korea. Hum. Genet. 74: 204-205, 1986. 2. Blake, N. M., Kirk, R. L. New genetic variant of 6-phosphogluconate dehydrogenase in Australian aborigines. Nature 221: 278 only, 1969. 3. Bowman, J. E., Carson, P. E., Frischer, H., De Garay, A. L. Genetics of starch-gel electrophoretic variants of human 6-phosphogluconic dehydrogenase: population and family studies in the United States and in Mexico. Nature 210: 811-812, 1966.

Uniprot ID: P52209

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 48 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 5226

Protein Name: 6-phosphogluconate dehydrogenase, decarboxylating

Gene Full Name: phosphogluconate dehydrogenase

Synonyms: 6PGD; PGD; PGDH; phosphogluconate dehydrogenase