Anti-PDZD8 Antibody Picoband®

SKU: A10427-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat
Immunofluorescence, 5 μg/ml, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: PDZD8

Specificity:

Background: Predicted to enable lipid binding activity and zinc ion binding activity. Involved in several processes, including mitochondrial calcium ion homeostasis; mitochondrion-endoplasmic reticulum membrane tethering; and regulation of cell morphogenesis. Located in endoplasmic reticulum membrane and mitochondria-associated endoplasmic reticulum membrane contact site.

Immunogen: E.coli-derived human PDZD8 recombinant protein (Position: R28-D1146). Human PDZD8 shares 86.4% amino acid (aa) sequence identity with mouse PDZD8.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Al-Amri, A. H., Armstrong, P., Amici, M., Ligneul, C., Rouse, J., El-Asrag, M. E., Pantiru, A., Vancollie, V. E., Ng, H. W. Y., Ogbeta, J. A., Goodchild, K., Ellegood, J., and 13 others. PDZD8 disruption causes cognitive impairment in humans, mice, and fruit flies. Biol. Psychiat. 92: 323-334, 2022. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/20/2011. 3. Henning, M. S., Morham, S. G., Goff, S. P., Naghavi, M. H. PDZD8 is a novel Gag-interacting factor that promotes retroviral infection. J. Virol. 84: 8990-8995, 2010.

Uniprot ID: Q8NEN9

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 150 kDa

Calculated Molecular Weight: 129 kDa

Gene ID: 118987

Protein Name: PDZ domain-containing protein 8

Gene Full Name: PDZ domain containing 8

Synonyms: PDZD8; PDZK8; PDZ domain-containing protein 8; Sarcoma antigen NY-SAR-84/NY-SAR-104