Anti-PAFAH1B2 Antibody Picoband®

SKU: A07067

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PAFAH1B2

Specificity:

Background: Platelet-activating factor acetylhydrolase IB subunit beta is an enzyme that in humans is encoded by the PAFAH1B2 gene. Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and LYSO-PAF. This gene encodes the beta subunit of PAFAH, the other subunits are alpha and gamma. Multiple alternatively spliced transcript variants have been described for this gene.

Immunogen: E.coli-derived human PAFAH1B2 recombinant protein (Position: D5-D190). Human PAFAH1B2 shares 99.5% amino acid (aa) sequence identity with both mouse and rat PAFAH1B2.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Adachi, H., Tsujimoto, M., Hattori, M., Arai, H., Inoue, K. Differential tissue distribution of the beta- and gamma-subunits of human cytosolic platelet-activating factor acetylhydrolase (isoform 1). Biochem. Biophys. Res. Commun. 233: 10-13, 1997. 2. Moro, F., Arrigo, G., Fogli, A., Bernard, L., Carrozzo, R. The beta and gamma subunits of the human platelet-activating factor acetyl hydrolase isoform Ib (PAFAH1B2 and PAFAH1B3) map to chromosome 11q23 and 19q13.1, respectively. Genomics 51: 157-159, 1998. 3. Tarricone, C., Perrina, F., Monzani, S., Massimiliano, L., Kim, M.-H., Derewenda, Z. S., Knapp, S., Tsai, L.-H., Musacchio, A. Coupling PAF signaling to dynein regulation: structure of LIS1 in complex with PAF-acetylhydrolase. Neuron 44: 809-821, 2004.

Uniprot ID: P68402

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 26 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 5049

Protein Name: Platelet-activating factor acetylhydrolase IB subunit alpha2

Gene Full Name: platelet activating factor acetylhydrolase 1b catalytic subunit 2

Synonyms: PAF AH 30 kDa subunit, PAF AH subunit beta, PAFAH subunit beta, PAFAH1B2, PAFAHB