Anti-NRD1/NRDC Antibody Picoband®

SKU: A05739-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: NRDC

Specificity:

Background: This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human NRD1/NRDC recombinant protein (Position: K427-R967).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Fumagalli, P., Accarino, M., Egeo, A., Scartezzini, P., Rappazzo, G., Pizzuti, A., Avvantaggiato, V., Simeone, A., Arrigo, G., Zuffardi, O., Ottolenghi, S., Taramelli, R. Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues. Genomics 47: 238-245, 1998. 2. Hospital, V., Prat, A., Joulie, C., Cherif, D., Day, R., Cohen, P. Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase family. Biochem. J. 327: 773-779, 1997. 3. Ohno, M., Hiraoka, Y., Matsuoka, T., Tomimoto, H., Takao, K., Miyakawa, T., Oshima, N., Kiyonari, H., Kimura, T., Kita, T., Nishi, E. Nardilysin regulates axonal maturation and myelination in the central and peripheral nervous system. Nature Neurosci. 12: 1506-1513, 2009.

Uniprot ID: O43847

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 140 kDa

Calculated Molecular Weight: 132 kDa

Gene ID: 4898

Protein Name: Nardilysin

Gene Full Name: nardilysin convertase

Synonyms: NRDC; NRD1; Nardilysin; N-arginine dibasic convertase; NRD convertase; NRD-C; Nardilysin convertase