Anti-NPY2R Antibody Picoband®

SKU: A04721-2

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC/IF,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: NPY2R

Specificity:

Background: Predicted to enable calcium channel regulator activity and neuropeptide Y receptor activity. Involved in cardiac left ventricle morphogenesis and outflow tract morphogenesis. Located in cilium. Implicated in Huntington's disease; morbid obesity; and obesity. Biomarker of peripheral artery disease and temporal lobe epilepsy.

Immunogen: E.coli-derived human NPY2R recombinant protein (Position: M1-K367). Human NPY2R shares 94.8% amino acid (aa) sequence identity with mouse NPY2R.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Ammar, D. A., Eadie, D. M., Wong, D. J., Ma, Y.-Y., Kolakowski, L. F., Jr., Yang-Feng, T. L., Thompson, D. A. Characterization of the human type 2 neuropeptide Y receptor gene (NPY2R) and localization to the chromosome 4q region containing the type 1 neuropeptide Y receptor gene. Genomics 38: 392-398, 1996. 2. Gerald, C., Walker, M. W., Vaysse, P. J.-J., He, C., Branchek, T. A., Weinshank, R. L. Expression cloning and pharmacological characterization of a human hippocampal neuropeptide Y/peptide YY Y2 receptor subtype. J. Biol. Chem. 270: 26758-26761, 1995. 3. Lovelace, J. W., Ma, J., Yadav, S., Chhabria, K., Shen, H., Pang, Z., Qi, T., Sehgal, R., Zhang, Y., Bali, T., Vaissiere, T., Tan, S., Liu, Y., Rumbaugh, G., Ye, L., Kleinfeld, D., Stringer, C., Augustine, V. Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope. Nature 623: 387-396, 2023.

Uniprot ID: P49146

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 43 kDa

Calculated Molecular Weight: 43 kDa

Gene ID: 4887

Protein Name: Neuropeptide Y receptor type 2

Gene Full Name: neuropeptide Y receptor Y2

Synonyms: NPY2R; Neuropeptide Y receptor type 2; NPY2-R; NPY-Y2 receptor; Y2 receptor