Anti-MINDY4 Antibody Picoband®

SKU: A32449-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: MINDY4

Specificity:

Background: MINDY lysine 48 deubiquitinase 4, also known as MINDY4, is a human gene. MINDY4 (MINDY Lysine 48 Deubiquitinase 4, also designated AQP1, AQP-1, CHIP28, C7orf67, and FAM188B) is a protein coding gene located on human chromosome 7p14.3. The human MINDY4 gene encodes a 757 amino acids protein containing 84372 Da. The MINDY4 protein is broadly expressed in testis, lung and other tissues. The MINDY4 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, and frog. 330 organisms have orthologs with human gene MINDY4. MINDY4B is an important paralog of this MINDY4 gene.

Immunogen: E.coli-derived human MINDY4 recombinant protein (Position: E414-Q685). Human MINDY4 shares 87.5% amino acid (aa) sequence identity with mouse MINDY4.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Urabe, Y., Tanikawa, C., Takahashi, A., Okada, Y., Morizono, T., Tsunoda, T., ... & Matsuda, K. (2012). A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35. 3, 7p14. 3, and 13q14. 1. PLoS genetics, 8(3), e1002541. 2. Choi, E. S., Lee, H., Sung, J. Y., Lee, C. H., Jang, H., Kim, K. T., ... & Goh, S. H. (2018). FAM188B enhances cell survival via interaction with USP7. Cell death & disease, 9(6), 633. 3. Kwasna, D., Rehman, S. A. A., Natarajan, J., Matthews, S., Madden, R., De Cesare, V., ... & Kulathu, Y. (2018). Discovery and characterization of ZUFSP/ZUP1, a distinct deubiquitinase class important for genome stability. Molecular cell, 70(1), 150-164.

Uniprot ID: Q4G0A6

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 72 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 84182

Protein Name: Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

Gene Full Name: MINDY lysine 48 deubiquitinase 4

Synonyms: MINDY4; C7orf67; FAM188B; Probable ubiquitin carboxyl-terminal hydrolase MINDY-4; Probable deubiquitinating enzyme MINDY-4