Anti-MAP1 Antibody (Monoclonal, HM-1)

SKU: MA1056

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: IHC,WB

Application Details: Immunohistochemistry (Paraffin-embedded Section), 1-2μg/ml, Mouse, rat
Immunohistochemistry (Frozen Section), 1-2μg/ml, Mouse, rat, -
Western blot, 0.5-2μg/ml, Mouse, rat

Gene Name: MAP1A

Specificity: No cross reactivity with other proteins.

Background: Microtubules are the ubiquitous cytoskeletal structural components that are involved in intracellular transport. They are composed of tubulin and microtubule-associated proteins (MAPs). MAP1 is one of the major neuronal MAPs as well as being the largest (350KD). MAPs include MAP1A, MAP1B, and MAP2. MAP1a is a single-copy gene spanning 10.5 kb. MAP1a coding sequence is contained in five exons. MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain.

Immunogen: Rat brain microtubule-associated proteins (MAPs).

Clonality: Monoclonal

Contents: Mouse IgG in stabilizing components, 1.2% sodium acetate and 0.01mg NaN3. *This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Ascites

Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Reference: 1. Fink, J. K.; Jones, S. M.; Esposito, C.; Wilkowski, J. : Human microtubule-associated protein 1a (MAP1A) gene: genomic organization, cDNA sequence, and developmental-and tissue-specific expression. Genomics 35: 577-585, 1996. 2. Ammarback, J. A.; Obar, R. A.; Hughes, S. M.; Vallee, R. B. : MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain. Neuron 7: 129-139, 1991.

Uniprot ID: P34926

Host: Mouse

Concentration: Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Mouse IgG1

Phospho_site:

Clone Number: Clone: HM-1

Observed Molecular Weight: 42 kDa

Calculated Molecular Weight: 299531 MW

Gene ID: Human(4130), Mouse(17754), Rat(25152)

Protein Name: Microtubule-associated protein 1A

Gene Full Name: microtubule-associated protein 1A

Synonyms: LC2, MAP1A; MAP1A protein; MAP1L; MTAP1A; MAP-1A