Anti-Lysozyme/LYZ Antibody Picoband®

SKU: A01811-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: LYZ

Specificity:

Background: This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis.

Immunogen: E.coli-derived human IMP4 recombinant protein (Position: L2-K236). Human IMP4 shares 97.9% amino acid (aa) sequence identity with both mouse and rat IMP4.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Camara, V. M., Harding, J. W., Prieur, D. J. Inherited lysozyme deficiency in rabbits: the absence of a primary isozyme of lysozyme as the cause of the condition. Lab. Invest. 63: 544-550, 1990. 2. Canet, D., Sunde, M., Last, A. M., Miranker, A., Spencer, A., Robinson, C. V., Dobson, C. M. Mechanistic studies of the folding of human lysozyme and the origin of amyloidogenic behavior in its disease-related variants. Biochemistry 38: 6419-6427, 1999. 3. Dayhoff, M. O. Lactalbumin and Lysozyme. Atlas of Protein Sequence and Structure. Vol. 5. Washington: National Biomedical Research Foundation (pub.) 1972. Pp. D133-D140.

Uniprot ID: P61626

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 15-17 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 4069

Protein Name: Lysozyme C

Gene Full Name: lysozyme

Synonyms: 1; 4 beta N acetylmuramidase C; lysozyme; lysozyme (renal amyloidosis); Lysozyme C; LYZ; LZM