Anti-LRP1B Antibody

SKU: A07425-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: IHC,ELISA

Application Details: Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5μg/ml, -

Gene Name: LRP1B

Specificity:

Background: Low-density lipoprotein receptor-related protein 1B is a protein that in humans is encoded by the LRP1B gene. This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer.

Immunogen: E.coli-derived human LRP1B recombinant protein (Position: D3704-K4547).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Liu, C.-X., Li, Y., Obermoeller-McCormick, L. M., Schwartz, A. L., Bu, G. The putative tumor suppressor LRP1B, a novel member of the low absorbance lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein. J. Biol. Chem. 276: 28889-28896, 2001. 2. Liu, C.-X., Musco, S., Lisitsina, N. M., Forgacs, E., Minna, J. D., Lisitsyn, N. A. LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines. Cancer Res. 60: 1961-1967, 2000. 3. Liu, C.-X., Musco, S., Lisitsina, N. M., Yaklichkin, S. Y., Lisitsyn, N. A. Genomic organization of a new candidate tumor suppressor gene, LRP1B. Genomics 69: 271-274, 2000.

Uniprot ID: Q9NZR2

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 92 kDa

Calculated Molecular Weight: 51200 MW

Gene ID: 53353

Protein Name: Low-density lipoprotein receptor-related protein 1B

Gene Full Name: LDL receptor related protein 1B

Synonyms: LRP1B; LRPDIT; Low-density lipoprotein receptor-related protein 1B; LRP-1B; Low-density lipoprotein receptor-related protein-deleted in tumor; LRP-DIT