Anti-LRIT3 Antibody Picoband®

SKU: A10719-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC,IF,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: LRIT3

Specificity:

Background: Leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 is a protein that in humans is encoded by the LRIT3 gene. This gene encodes a protein that has a fibronectin type III domain and a C-terminal transmembrane domain, as well as a leucine-rich repeat domain and immunoglobulin-like domain near the N-terminus. The encoded protein may regulate fibroblast growth factor receptors and affect the modification of these receptors, which are glycosylated differently in the Golgi and endoplasmic reticulum. Mutations in this gene are associated with congenital stationary night blindness, type 1F.

Immunogen: E.coli-derived human LRIT3 recombinant protein (Position: E50-R573).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Hartz, P. A. Personal Communication. Baltimore, Md. 1/4/2013. 2. Kim, S.-D., Liu, J. L., Roscioli, T., Buckley, M. F., Yagnik, G., Boyadjiev, S. A., Kim, J. Leucine-rich repeat, immunoglobulin-like and transmembrane domain 3 (LRIT3) is a modulator of FGFR1. FEBS Lett. 586: 1516-1521, 2012. 3. Neuille, M., El Shamieh, S., Orhan, E., Michiels, C., Antonio, A., Lancelot, M.-E., Condroyer, C., Bujakowska, K., Poch, O., Sahel, J.-A., Audo, I., Zeitz, C. Lrit3 deficient mouse (nob6): a novel model of complete congenital stationary night blindness (cCSNB). PLoS One 9: e90342, 2014. Note: Electronic Article.

Uniprot ID: Q3SXY7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 75 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 345193

Protein Name: Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3

Gene Full Name: leucine rich repeat, Ig-like and transmembrane domains 3

Synonyms: LRIT3; Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3