Anti-L1RE1 Antibody Picoband®

SKU: A13161

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: L1RE1

Specificity:

Background: Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. May function as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.

Immunogen: E.coli-derived human L1RE1 recombinant protein (Position: Q147-E324).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Baillie, J. K., Barnett, M. W., Upton, K. R., Gerhardt, D. J., Richmond, T. A., De Sapio, F., Brennan, P., Rizzu, P., Smith, S., Fell, M., Talbot, R. T., Gustincich, S., Freeman, T. C., Mattick, J. S., Hume, D. A., Heutink, P., Carninci, P., Jeddeloh, J. A., Faulkner, G. J. Somatic retrotransposition alters the genetic landscape of the human brain. Nature 479: 534-537, 2011. 2. Boeke, J. D. LINEs and Alus--the polyA connection. Nature Genet. 16: 6-7, 1997. 3. Brosius, J., Gould, S. J. On 'genomenclature': a comprehensive (and respectful) taxonomy for pseudogenes and other 'junk DNA.' Proc. Nat. Acad. Sci. 89: 10706-10710, 1992.

Uniprot ID: Q9UN81

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 40 kDa

Calculated Molecular Weight: 9700 MW

Gene ID: 4029

Protein Name: LINE-1 retrotransposable element ORF1 protein

Gene Full Name: LINE1 retrotransposable element 1

Synonyms: L1RE1; LRE1; LINE-1 retrotransposable element ORF1 protein; L1ORF1p; LINE retrotransposable element 1; LINE1 retrotransposable element 1