Anti-IMMP2L Antibody Picoband®

SKU: A08704-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC/IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: IMMP2L

Specificity:

Background: This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene.

Immunogen: E.coli-derived human IMMP2L recombinant protein (Position: M1-E175). Human IMMP2L shares 91.4% amino acid (aa) sequence identity with mouse IMMP2L.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Boghosian-Sell, L., Comings, D. E., Overhauser, J. Tourette syndrome in a pedigree with a 7;18 translocation: identification of a YAC spanning the translocation breakpoint at 18q22.3. Am. J. Hum. Genet. 59: 999-1005, 1996. 2. Burri, L., Strahm, Y., Hawkins, C. J., Gentle, I. E., Puryer, M. A., Verhagen, A., Callus, B., Vaux, D., Lithgow, T. Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membrane. Molec. Biol. Cell 16: 2926-2933, 2005. 3. Petek, E., Windpassinger, C., Vincent, J. B., Cheung, J., Boright, A. P., Scherer, S. W., Kroisel, P. M., Wagner, K. Disruption of a novel gene (IMMP2L) by a breakpoint in 7q31 associated with Tourette syndrome. Am. J. Hum. Genet. 68: 848-858, 2001.

Uniprot ID: Q96T52

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 23 kDa

Calculated Molecular Weight: 20 kDa

Gene ID: 83943

Protein Name: Mitochondrial inner membrane protease subunit 2

Gene Full Name: inner mitochondrial membrane peptidase subunit 2

Synonyms: IMMP2L; Mitochondrial inner membrane protease subunit 2; EC 3.4.21.-; IMP2-like protein