Anti-FNDC5 Antibody Picoband®

SKU: A02538-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,WB

Application Details: Western blot, 0.1-0.5μg/ml
ELISA, 0.1-0.5μg/ml

Gene Name: FNDC5

Specificity: No cross reactivity with other proteins.

Background: Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene. This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants.

Immunogen: E. coli-derived human FNDC5 recombinant protein (Position: D32-E143).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Erickson HP (October 2013). Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?. Adipocyte. 2 (4): 289–93. 2. Staiger, H., Bohm, A., Scheler, M., Berti, L., Machann, J., Schick, F., Machicao, F., Fritsche, A., Stefan, N., Weigert, C., Krook, A., Haring, H.-U., de Angelis, M. H. Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity. PLoS One 8: e61903, 2013.

Uniprot ID: Q8NAU1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 23 kDa

Calculated Molecular Weight:

Gene ID: 252995

Protein Name: Fibronectin type III domain-containing protein 5

Gene Full Name: fibronectin type III domain containing 5

Synonyms: FNDC5; FRCP2; Irisin