Anti-ETV6/Tel Antibody Picoband®

SKU: A00361-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Rat

Applications: ELISA,ICC/IF,IHC,WB

Application Details: Western blot, 0.1-0.5μg/ml, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: ETV6

Specificity: No cross reactivity with other proteins.

Background: Transcription factor ETV6 is a protein that in humans is encoded by the ETV6 gene. This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Immunogen: E. coli-derived human ETV6/Tel recombinant protein (Position: E327-Q448).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: ETV6 ets variant gene 6 (TEL oncogene). 2. Chiosea SI, Griffith C, Assaad A, Seethala RR (Sep 2012). Clinicopathological characterization of mammary analogue secretory carcinoma of salivary glands. Histopathology. 61 (3): 387–94.

Uniprot ID: P41212

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 53-60 kDa

Calculated Molecular Weight: 53 kDa

Gene ID: 2120

Protein Name: Transcription factor ETV6

Gene Full Name: ETS variant transcription factor 6

Synonyms: ETS related protein Tel1; ETS translocation variant 6; ets variant 6; ETV6; TEL; TEL/ABL; TEL1; Transcription factor ETV6