Anti-ERVW-1 Antibody Picoband®

SKU: PB9622

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: WB

Application Details: Western blot, 0.1-0.5μg/ml, Human

Gene Name: ERVW-1

Specificity: No cross reactivity with other proteins.

Background: ERVW-1 is also known as ERVWE1. The human ERVWE1 locus is derived from a human endogenous retrovirus-W (HERV-W) provirus located on chromosome 7. This provirus has inactivating mutations in the gag and pol genes, but the envelope glycoprotein gene has been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ERVW-1.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: ERVWE1 endogenous retroviral family W, env(C7), member 1 (syncytin). 2. Li F, Nellåker C, Sabunciyan S, Yolken RH, Jones-Brando L, Johansson AS, Owe-Larsson B, Karlsson H. “Transcriptional derepression of the ERVWE1 locus following influenza A virus infection.” J Virol, 2014 Apr.

Uniprot ID: Q9UQF0

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 80 kDa

Calculated Molecular Weight: 59866 MW

Gene ID: 30816

Protein Name: Syncytin-1

Gene Full Name: endogenous retrovirus group W member 1, envelope

Synonyms: env; Env W; Envelope polyprotein gPr73; Enverin; ERVW-1; ERVWE1; gp24; gp50 Transmembrane protein; HERV 7q; HERV 7q Envelope protein; HERV W; HERV W ENV; HERV W envelope protein; HERVW; Surface protein; SU; syncytin; Syncytin 1; Syncytin-1; Transmembrane protein; TM