Anti-CXCL16 Antibody Picoband®

SKU: PB10054

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: ELISA (Cap),WB

Application Details: Western blot, 0.1-0.5μg/ml, Human
ELISA(Cap) , 1-5μg/ml, Human, -

Gene Name: CXCL16

Specificity: No cross reactivity with other proteins.

Background: CXCL16, Chemokine (C-X-C motif) ligand 16, is a small cytokine belonging to the CXC chemokine family. Larger than other chemokines (with 254 amino acids), CXCL16 is composed of a CXC chemokine domain, a mucin-like stalk, a transmembrane domain and a cytoplasmic tail containing a potential tyrosine phosphorylation site that may bind SH2. By somatic cell hybrid analysis, the CXCL16 gene is mapped to 17p13, a locus separate from all other known chemokines. Chemotaxis assays found that CXCL16 induced a strong chemotactic response in activated CD8 T cells. In addition, CXCL16 induced calcium mobilization.

Immunogen: E. coli-derived human CXCL16 recombinant protein (Position: N30-A196). Human CXCL16 shares 47% and 45.7% amino acid (aa) sequence identity with mouse and rat CXCL16, respectively.

Clonality: Polyclonal

Contents: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg NaN3.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Matloubian, M., David, A., Engel, S., Ryan, J. E., Cyster, J. G.A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.Nature Immun. 1: 298-304, 2000. 2. Shimaoka, T., Kume, N., Minami, M., Hayashida, K., Kataoka, H., Kita, T., Yonehara, S.Molecular cloning of a novel scavenger receptor for oxidized low absorbance lipoprotein, SR-PSOX, on macrophages.J. Biol. Chem. 275: 40663-40666, 2000. 3. Wilbanks, A., Zondlo, S. C., Murphy, K., Mak, S., Soler, D., Langdon, P., Andrew, D. P., Wu, L., Briskin, M.Expression cloning of the STRL33/BONZO/TYMSTR ligand reveals elements of CC, CXC, CX3C chemokines.J. Immun. 166: 5145-5154, 2001.

Uniprot ID: Q9H2A7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 35 kDa

Calculated Molecular Weight: 27579 MW

Gene ID: 58191

Protein Name: C-X-C motif chemokine 16

Gene Full Name: C-X-C motif chemokine ligand 16

Synonyms: C X C motif chemokine 16; CXCL16; CXCLG16; SCYB16; Small inducible cytokine B16; SR PSOX; SRPSOX; Transmembrane chemokine CXCL16