Anti-Calponin 2/CNN2 Antibody Picoband®

SKU: A08680-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: Flow Cytometry,IHC,WB

Application Details: Western blot, 0.1-0.25 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Gene Name: CNN2

Specificity:

Background: Calponin 2 is a protein that in humans is encoded by the CNN2 gene. The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Calponin 2/CNN2, which shares 75% amino acid (aa) sequence identity with mouse CNN2.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Cheng, J.-F., Boyartchuk, V., Zhu, Y. Isolation and mapping of human chromosome 21 cDNA: progress in constructing a chromosome 21 expression map. Genomics 23: 75-84, 1994. 2. Gross, M. B. Personal Communication. Baltimore, Md. 2/16/2011. 3. Masuda, H., Tanaka, K., Takagi, M., Ohgami, K., Sakamaki, T., Shibata, N., Takahashi, K. Molecular cloning and characterization of human non-smooth muscle calponin. J. Biochem. 120: 415-424, 1996.

Uniprot ID: Q99439

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 34 kDa

Calculated Molecular Weight: 36881 MW

Gene ID: 1265

Protein Name: Calponin-2

Gene Full Name: calponin 2

Synonyms: calponin 2; Calponin H2; smooth muscle; CNN2; Neutral calponin