Anti-BPNT2 Antibody Picoband®

SKU: A11341-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.1-0.25 μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: BPNT2

Specificity:

Background: This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1.

Immunogen: E.coli-derived human BPNT2 recombinant protein (Position: D62-E354). Human BPNT2 shares 93.2% and 93.5% amino acid (aa) sequence identity with mouse and rat BPNT2, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Frederick, J. P., Tafari, A. T., Wu, S.-M., Megosh, L. C., Chiou, S.-T., Irving, R. P., York, J. D. A role for a lithium-inhibited Golgi nucleotidase in skeletal development and sulfation. Proc. Nat. Acad. Sci. 105: 11605-11612, 2008. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 5/26/2011. 3. Kiper, P. O. S., Utine, G. E., Boduroglu, K., Alanay, Y. Catel-Manzke syndrome: a clinical report suggesting autosomal recessive inheritance. Am. J. Med. Genet. 155: 2288-2292, 2011.

Uniprot ID: Q9NX62

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 42 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 54928

Protein Name: Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

Gene Full Name: 3'(2'), 5'-bisphosphate nucleotidase 2

Synonyms: IMPAD1; IMPA3; Golgi-resident adenosine 3';5'-bisphosphate 3'-phosphatase; Golgi-resident PAP phosphatase; gPAPP; Inositol monophosphatase domain-containing protein 1; Myo-inositol monophosphatase A3; Phosphoadenosine phosphate 3'-nucleotidase