Anti-Atg4A Monoclonal Antibody

SKU: M06539

Size: 100 μl

Storage: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Form: Liquid

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,IP

Application Details: WB 1:500-2000
IHC 1:50-200
IP 1:20

Gene Name: ATG4A

Specificity:

Background:

Immunogen: A synthesized peptide derived from human Atg4A The cysteine protease Atg4 is pivotal to autophagosome membrane generation and regulation. Atg4 primes the Atg8 homologue for lipidation by cleaving its carboxy terminus and exposing its glycine residue for E1-like enzyme Atg7. The Atg8 homologue is transferred to the E2-like enzyme Atg3 before forming the Atg8-PE conjugate. During later stages of autophagy, Atg4 can reverse this lipidation event by cleaving PE, thereby recycling the Atg8 homologue.

Clonality: Monoclonal

Contents: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Affinity-chromatography

Reconstitution:

Reference:

Uniprot ID: Q8WYN0

Host: Rabbit

Concentration: 0.5mg/ml

Conjugate:

Cross Reactivity:

Isotype: Rabbit IgG

Phospho_site:

Clone Number: Clone: ACHB-1

Observed Molecular Weight: 45 kDa

Calculated Molecular Weight: 22745 MW

Gene ID: 115201

Protein Name: Cysteine protease ATG4A

Gene Full Name: autophagy related 4A cysteine peptidase

Synonyms: APG4A; ATG4A; AUTL2; Autophagin 2; Cysteine protease ATG4A; hAPG4A