Anti-Aldolase C/ALDOC Antibody Picoband®

SKU: A05296-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: IHC,WB

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Rat

Gene Name: ALDOC

Specificity:

Background: Aldolase C, fructose-bisphosphate (ALDOC, or ALDC), is an enzyme that, in humans, is encoded by the ALDOC gene on chromosome 17. This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Aldolase C/ALDOC, which shares 100% and 93.8% amino acid (aa) sequence identity with mouse and rat ALDOC, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Buono, P., Paolella, G., Mancini, F. P., Izzo, P., Salvatore, F. The complete nucleotide sequence of the gene coding for the human aldolase C. Nucleic Acids Res. 16: 4733 only, 1988. 2. Rocchi, M., Vitale, E., Covone, A., Romeo, G., Santamaria, R., Buono, P., Paolella, G., Salvatore, F. Assignment of human aldolase C gene to chromosome 17, region cen--q21.1. Hum. Genet. 82: 279-282, 1989. 3. Rottmann, W. H., Deselms, K. R., Niclas, J., Camerato, T., Holman, P. S., Green, C. J., Tolan, D. R. The complete amino acid sequence of the human aldolase C isozyme derived from genomic clones. Biochimie 69: 137-145, 1987.

Uniprot ID: P09972

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 39 kDa

Calculated Molecular Weight: 39411 MW

Gene ID: 230

Protein Name: Fructose-bisphosphate aldolase C

Gene Full Name: aldolase, fructose-bisphosphate C

Synonyms: ALDOC; Aldolase C; Brain type aldolase; Fructose bisphosphate aldolase C